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本产品仅用于科研,不用于临床
英文名称 Anti-Eppin
中文名称 附睾蛋白酶抑制蛋白
别 名 SPINLW1; WAP7; WFDC7; Variant; Cancer/testis antigen 71; CT71; Epididymal protease inhibitor; Protease inhibitor WAP7; Serine protease inhibitor-like with Kunitz and WAP domains 1; EPPI_MOUSE; WAPfour-disulfide core domain protein 7.
浓 度 1mg/1ml
说 明 书 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Mouse, Rat
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学 发育生物学 生长因子和激素 转录调节因子 泛素
蛋白分子量 predicted molecular weight: 13kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from mouse Eppin
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and omeric. This gene is a member of the WFDC gene family and belongs to the omeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. [provided by RefSeq].
Function : Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility (By similarity).
Subunit : Monomer (By similarity). Homodimer (By similarity). Homomultimers (By similarity). Interacts (via C-terminus) with SEMG1 (via 164-283 AA) (By similarity). Interacts with LTF (By similarity). Found in a complex with LTF, CLU, EPPIN and SEMG1 (By similarity).
Subcellular Location : Secreted. Cell surface. Note=Present on the surface of spermatozoa both before and after capacitation.
Tissue Specificity : Expressed in differentiated spermatogonia in testis. Expressed in spermatogonia cell lines GC-1 spg and GC-2spd(ts) as well as in the Leydig tumor cell line MLTC-1 (at protein level). Expressed specifically in epididymis and testis. Expressed predominantly on the postacrosomal region of mouse spermatozoa, in Sertoli cells, Leydig cells, and round spermatids in the testis, and in the principal cells of the cauda epididymidis epithelium.
Similarity : Contains 1 BPTI/Kunitz inhibitor domain.
Contains 1 WAP domain.
Database links : UniProtKB/Swiss-Prot: Q9DA01.1
附睾蛋白酶抑制蛋白(Eppin)是一种睾丸/附睾特异性蛋白,可能与精子在附睾的成熟密切相关.
宿主:Human、Murine、Rat (Rattus)、Bovine、Dog (Canine)等物种
应用范围: WB, ELISA, IP, IHC (p), IHC (f), IF
缓冲液:0.01m PBS,pH值7.4和10毫克/毫升BSA
储存液:0.1%(w/v)*
甲状腺过氧化物酶(TPO)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Thyroid Peroxidase (TPO)48T/96TY08435Mus musculus (Mouse)
血管活性肠肽(VIP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Vasoactive Intestinal Peptide (VIP)48T/96TY08436Homo sapiens (Human)
血管活性肠肽(VIP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Vasoactive Intestinal Peptide (VIP)48T/96TY08437Rattus norvegicus (Rat)
血管活性肠肽(VIP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Vasoactive Intestinal Peptide (VIP)48T/96TY08438Mus musculus (Mouse)
P物质(SP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Substance P (SP)48T/96TY08439Homo sapiens (Human)
抗酒石酸酸性磷酸酶(ACP5)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Acid Phosphatase 5, Tartrate Resistant (ACP5)48T/96TY08440Homo sapiens (Human)
抗酒石酸酸性磷酸酶(ACP5)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Acid Phosphatase 5, Tartrate Resistant (ACP5)48T/96TY08441Rattus norvegicus (Rat)
抗酒石酸酸性磷酸酶(ACP5)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Acid Phosphatase 5, Tartrate Resistant (ACP5)48T/96TY08442Mus musculus (Mouse)
脂蛋白脂酶(LIPD)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Lipase, Lipoprotein (LIPD)48T/96TY08443Homo sapiens (Human)
载脂蛋白H(APOH)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Apolipoprotein H (APOH)48T/96TY08444Rattus norvegicus (Rat)
载脂蛋白H(APOH)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Apolipoprotein H (APOH)48T/96TY08445Mus musculus (Mouse)
C反应蛋白(CRP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for C Reactive Protein (CRP)48T/96TY08446Homo sapiens (Human)
基质细胞衍生因子4(SDF4)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Stromal Cell Derived Factor 4 (SDF4)48T/96TY08447Homo sapiens (Human)
基质细胞衍生因子4(SDF4)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Stromal Cell Derived Factor 4 (SDF4)48T/96TY08448Rattus norvegicus (Rat)
基质细胞衍生因子4(SDF4)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Stromal Cell Derived Factor 4 (SDF4)48T/96TY08449Mus musculus (Mouse)
周期素依赖性激酶抑制因子2A(CDKN2A)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin Dependent Kinase Inhibitor 2A (CDKN2A)48T/96TY08450Homo sapiens (Human)
周期素依赖性激酶抑制因子2A(CDKN2A)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin Dependent Kinase Inhibitor 2A (CDKN2A)48T/96TY08451Rattus norvegicus (Rat)
周期素依赖性激酶抑制因子2A(CDKN2A)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin Dependent Kinase Inhibitor 2A (CDKN2A)48T/96TY08452Mus musculus (Mouse)
淀粉酶γ(Amyγ)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Amylase Gamma (Amyg)48T/96TY08453Homo sapiens (Human)
唾液淀粉酶α1(AMY1)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Amylase Alpha 1, Salivary (AMY1)48T/96TY08454Rattus norvegicus (Rat)
组织因子通道抑制因子(TFPI)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI)48T/96TY08455Mus musculus (Mouse)
组织因子通道抑制因子(TFPI)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Tissue Factor Pathway Inhibitor (TFPI)48T/96TY08456Oryctolagus cuniculus (Rabbit)
磷脂酶A2激活蛋白(PLAA)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Phospholipase A2 Activating Protein (PLAA)48T/96TY08457Rattus norvegicus (Rat)
磷脂酶A2激活蛋白(PLAA)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Phospholipase A2 Activating Protein (PLAA)48T/96TY08458Mus musculus (Mouse)
血红素氧合酶1(HO1)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Heme Oxygenase 1, Decycling (HO1)48T/96TY08459Homo sapiens (Human)
血红素氧合酶1(HO1)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Heme Oxygenase 1, Decycling (HO1)48T/96TY08460Rattus norvegicus (Rat)
血红素氧合酶1(HO1)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Heme Oxygenase 1, Decycling (HO1)48T/96TY08461Mus musculus (Mouse)
糖抗原125(CA125)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Carbohydrate Antigen 125 (CA125)48T/96TY08462Mus musculus (Mouse)
激肽释放酶3(KLK3)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Kallikrein 3 (KLK3)48T/96TY08463Rattus norvegicus (Rat)
激肽释放酶3(KLK3)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Kallikrein 3 (KLK3)48T/96TY08464Mus musculus (Mouse)
前列腺酸性磷酸酶(ACP3)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Acid Phosphatase 3, Prostatic (ACP3)48T/96TY08465Rattus norvegicus (Rat)
前列腺酸性磷酸酶(ACP3)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Acid Phosphatase 3, Prostatic (ACP3)48T/96TY08466Mus musculus (Mouse)
甲胎蛋白(αFP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Alpha-Fetoprotein (aFP)48T/96TY08467Rattus norvegicus (Rat)
甲胎蛋白(αFP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Alpha-Fetoprotein (aFP)48T/96TY08468Mus musculus (Mouse)
髓鞘碱性蛋白(MBP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Myelin Basic Protein (MBP)48T/96TY08469Homo sapiens (Human)
髓鞘碱性蛋白(MBP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Myelin Basic Protein (MBP)48T/96TY08470Rattus norvegicus (Rat)
髓鞘碱性蛋白(MBP)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Myelin Basic Protein (MBP)48T/96TY08471Mus musculus (Mouse)
细胞周期素D1(CCND1)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D1 (CCND1)48T/96TY08472Homo sapiens (Human)
细胞周期素D1(CCND1)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D1 (CCND1)48T/96TY08473Rattus norvegicus (Rat)
细胞周期素D1(CCND1)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D1 (CCND1)48T/96TY08474Mus musculus (Mouse)
细胞周期素D2(CCND2)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D2 (CCND2)48T/96TY08475Homo sapiens (Human)
细胞周期素D2(CCND2)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D2 (CCND2)48T/96TY08476Rattus norvegicus (Rat)
细胞周期素D2(CCND2)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D2 (CCND2)48T/96TY08477Mus musculus (Mouse)
细胞周期素D3(CCND3)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D3 (CCND3)48T/96TY08478Homo sapiens (Human)
细胞周期素D3(CCND3)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D3 (CCND3)48T/96TY08479Rattus norvegicus (Rat)
细胞周期素D3(CCND3)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Cyclin D3 (CCND3)48T/96TY08480Mus musculus (Mouse)
热休克蛋白β2(HSPβ2)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Heat Shock Protein Beta 2 (HSPb2)48T/96TY08481Homo sapiens (Human)
热休克蛋白40(HSP40)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Heat Shock Protein 40 (HSP40)48T/96TY08482Homo sapiens (Human)
热休克蛋白90(HSP90)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Heat Shock Protein 90 (HSP90)48T/96TY08483Homo sapiens (Human)
淀粉样蛋白β1-40(Aβ1-40)检测试剂盒(酶联免疫吸附试验法)ELISA Kit for Amyloid Beta Peptide 1-40 (Ab1-40)48T/96TY08484Homo sapiens (Human)