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本产品仅用于科研，不用于临床

英文名称 Anti-ERMAP
中文名称 红细胞膜相关蛋白ERMAP抗体
别 名 ERMAP; ERMAP_HUMAN; Erythroblast membrane associated protein; Erythroid membrane associated protein; Erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; MGC118812; MGC118813; PRO2801; Radin blood group （Rd）; Radin blood group antigen; RD; SC; Scianna blood group （Sc）; Scianna blood group antigen.
浓 度 1mg/1ml
说 明 书 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat
产品类型 一抗
研究领域 细胞生物 发育生物学 信号转导 干细胞 细胞膜蛋白
蛋白分子量 predicted molecular weight: 50kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human ERMAP
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin （Sc/Rd） blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce antibodies against the fetal blood. This condition is known as hemolytic disease of the newborn （HDN） and is characterized by jaundice, anemia and in some cases, infant death.
Function : Possible role as a cell-adhesion or receptor molecule of erythroid cells.
Subcellular Location : Cell membrane. Cytoplasm.
Tissue Specificity : Expressed in erythroid-enriched bone marrow （at protein level）. Highly expressed in bone marrow and to a lower extent in leukocytes, thymus, lymph node and spleen.
Post-translational modifications : Glycosylated.
Similarity : Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 B30.2/SPRY domain.
Contains 1 Ig-like V-type （immunoglobulin-like） domain.
Database links : UniProtKB/Swiss-Prot: Q96PL5.1

宿主：Human、Murine、Rat （Rattus）、Bovine、Dog （Canine）等物种
红细胞膜相关蛋白ERMAP抗体  应用范围: WB, ELISA, IP, IHC （p）, IHC （f）, IF
缓冲液：0.01m PBS,pH值7.4和10毫克/毫升BSA
储存液：0.1%（w/v）

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